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Shlomo Melmed Selected Research

Growth Hormone (Somatotropin)

1/2022Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement.
1/2022Maintenance of response to oral octreotide compared with injectable somatostatin receptor ligands in patients with acromegaly: a phase 3, multicentre, randomised controlled trial.
11/2021International Multicenter Validation Study of the SAGIT® Instrument in Acromegaly.
8/2021Insulin-like Growth Factor 1 and Prolactin Levels in Chimpanzees (Pan troglodytes) Across the Lifespan.
11/2020DNA damage and growth hormone hypersecretion in pituitary somatotroph adenomas.
10/2019Staging and managing patients with acromegaly in clinical practice: baseline data from the SAGIT® validation study.
1/2019Acromegaly.
2/2017Somatostatin and dopamine receptor regulation of pituitary somatotroph adenomas.
1/2017Androgen Receptor Regulation of Local Growth Hormone in Prostate Cancer Cells.
6/2016Growth hormone is permissive for neoplastic colon growth.
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Shlomo Melmed Research Topics

Disease

62Neoplasms (Cancer)
01/2022 - 01/2000
55Pituitary Neoplasms (Pituitary Adenoma)
01/2022 - 01/2000
39Acromegaly
01/2022 - 01/2002
21Adenoma (Adenomas)
11/2022 - 01/2000
12Pituitary ACTH Hypersecretion
01/2022 - 11/2002
11Prolactinoma (Prolactinomas)
01/2021 - 02/2003
10Carcinogenesis
01/2022 - 01/2002
9Growth Hormone-Secreting Pituitary Adenoma
01/2022 - 01/2000
6Hyperplasia
10/2012 - 01/2002
5ACTH-Secreting Pituitary Adenoma
01/2021 - 11/2002
4Cushing Syndrome
09/2018 - 05/2011
3Ataxia Telangiectasia (Louis Bar Syndrome)
02/2019 - 12/2012
3Inflammation (Inflammations)
01/2019 - 05/2002
3Carcinoid Tumor (Carcinoid)
09/2018 - 12/2007
3Body Weight (Weight, Body)
02/2017 - 08/2008
2Neoplasm Metastasis (Metastasis)
01/2022 - 10/2003
2Carcinoma (Carcinomatosis)
01/2021 - 05/2009
2Injection Site Reaction
02/2016 - 09/2008
2Hypogonadism (Hypergonadotropic Hypogonadism)
06/2015 - 08/2014
2Chromosomal Instability (Chromosome Stability)
08/2013 - 12/2012
2Hyperprolactinemia
02/2011 - 07/2006
2Colonic Neoplasms (Colon Cancer)
01/2011 - 03/2008
2Pituitary Diseases (Disease, Anterior Pituitary)
03/2010 - 02/2008
2Aneuploidy (Aneuploid)
11/2008 - 11/2003
2Headache (Headaches)
09/2008 - 07/2006
2Neuroendocrine Tumors (Neuroendocrine Tumor)
05/2008 - 12/2007
2Hypopituitarism (Sheehan's Syndrome)
10/2003 - 05/2003
1Fibrosis (Cirrhosis)
01/2022
1Delayed Puberty
08/2021
1Bradycardia
01/2021
1Exanthema (Rash)
01/2021

Drug/Important Bio-Agent (IBA)

31Growth Hormone (Somatotropin)IBA
01/2022 - 01/2000
22Insulin-Like Growth Factor I (IGF-1)IBA
01/2022 - 01/2002
20Hormones (Hormone)IBA
11/2022 - 05/2003
18LigandsIBA
01/2022 - 05/2003
18Adrenocorticotropic Hormone (ACTH)FDA Link
01/2021 - 05/2002
18Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
02/2017 - 01/2000
14ProlactinIBA
01/2015 - 01/2002
13Octreotide (Sandostatin)FDA LinkGeneric
01/2022 - 01/2000
13Somatostatin Receptors (Somatostatin Receptor)IBA
01/2022 - 06/2004
12Messenger RNA (mRNA)IBA
01/2022 - 01/2000
10Proteins (Proteins, Gene)FDA Link
01/2022 - 02/2003
9SecurinIBA
12/2012 - 03/2003
8lanreotide (Somatuline)FDA Link
01/2022 - 01/2002
7Pro-Opiomelanocortin (Proopiomelanocortin)IBA
01/2021 - 05/2011
7Pharmaceutical PreparationsIBA
07/2015 - 10/2003
6Dopamine Agonists (Dopamine Agonist)IBA
01/2021 - 10/2003
6Insulin (Novolin)FDA Link
10/2019 - 10/2006
5Insulin-Like PeptidesIBA
01/2022 - 03/2008
5Tyrosine Kinase InhibitorsIBA
01/2021 - 10/2011
5Hydrocortisone (Cortisol)FDA LinkGeneric
09/2018 - 08/2014
5pasireotideIBA
02/2017 - 06/2004
5ErbB Receptors (EGF Receptor)IBA
02/2017 - 01/2006
5Estrogens (Estrogen)FDA Link
10/2012 - 01/2002
4Biomarkers (Surrogate Marker)IBA
01/2022 - 10/2003
4pegvisomantFDA LinkGeneric
01/2020 - 01/2002
4CorticosteroneIBA
02/2017 - 11/2002
4Dopamine (Intropin)FDA LinkGeneric
02/2017 - 11/2003
4Transcription Factors (Transcription Factor)IBA
06/2016 - 04/2010
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2015 - 10/2005
4Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
04/2014 - 04/2003
4CytokinesIBA
03/2009 - 05/2002
3DNA (Deoxyribonucleic Acid)IBA
01/2022 - 12/2006
3Lapatinib (GW572016)FDA Link
01/2021 - 01/2011
3Phosphotransferases (Kinase)IBA
02/2019 - 12/2012
3Gefitinib (Iressa)FDA Link
02/2017 - 08/2008
3GlucocorticoidsIBA
07/2015 - 11/2002
3somatostatin receptor 2IBA
01/2015 - 06/2004
3Epidermal Growth Factor (EGF)IBA
04/2014 - 08/2008
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2008 - 10/2003
3Leukemia Inhibitory FactorIBA
03/2006 - 05/2002
3PlasticsIBA
03/2006 - 12/2003
2RoscovitineIBA
07/2015 - 05/2011
2Cyclin EIBA
07/2015 - 05/2011
2ClusterinIBA
12/2012 - 03/2011
2TBR-760IBA
10/2012 - 12/2007
2Biological ProductsIBA
09/2012 - 11/2005
2Glucose (Dextrose)FDA LinkGeneric
12/2011 - 02/2009
2Cyclin-Dependent Kinases (cdk Proteins)IBA
05/2011 - 02/2006
2Luteinizing Hormone (Lutropin)FDA LinkGeneric
05/2011 - 05/2003
2Follicle Stimulating Hormone (Follitropin)FDA Link
05/2011 - 04/2008
2SteroidsIBA
01/2010 - 09/2008
2aryl hydrocarbon receptor-interacting proteinIBA
05/2007 - 12/2006
2enhanced green fluorescent proteinIBA
10/2006 - 11/2003
2Glycoproteins (Glycoprotein)IBA
10/2006 - 05/2005
2Rosiglitazone (Avandia)FDA Link
05/2003 - 11/2002
2PPAR gammaIBA
05/2003 - 11/2002
2Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
05/2003 - 11/2002
2ThiazolidinedionesIBA
05/2003 - 11/2002
1Mitogen-Activated Protein KinasesIBA
01/2022
1OsilodrostatIBA
01/2022
1Therapeutic UsesIBA
01/2022
1Actin Depolymerizing Factors (Cofilins)IBA
01/2022
14-O-carboxymethylascochlorinIBA
01/2021
1Growth Factor ReceptorsIBA
01/2021

Therapy/Procedure

34Therapeutics
11/2022 - 01/2000
5Drug Therapy (Chemotherapy)
05/2011 - 03/2003
4Injections
01/2022 - 05/2008
4Radiotherapy
12/2021 - 07/2005
2Subcutaneous Injections
05/2003 - 11/2002